Offerte Lavoro Other 2026 | Euspert

Senior Principal Statistician (Hiring Immediately)

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide. Please visit www.jazzpharmaceuticals.com for more information.

Brief Description:

The Senior Principal Statistician, Biostatistics will be a lead statistician on individual studies, across related studies, and for integrated summaries and will design and report Phase I to IV clinical studies and regulatory filings under the supervision of a more senior statistician. This role is responsible for all statistical aspects of study design, study analysis and validation, and study documentation. The Senior Principal Statistician will provide timely and scientifically sound statistical expertise to clinical development projects and develop and execute statistical strategy, design, and analyses for clinical trials. This position will work collaboratively with clinical development, pharmacology, pharmacovigilance, clinical drug supply, project management, regulatory affairs, medical writing, clinical data management, and clinical operations. The Senior Principal Statistician will manage work done by statistics and programming external vendors.

Essential Functions

Participate in department and cross-functional meetings to optimize clinical study designs, endpoints, and analysis strategies in protocols.
Collaborate with cross-functional team members to meet study any recurring report timelines.
Support the development and implementation of study protocols.
Review and provide input to data capture systems and participate in their validation.
Develop statistical programs as necessary to simulate clinical trial design operating characteristics, perform analysis, prepare data displays, verify data accuracy and validity of analyses performed by statistical programming.
Write statistical analysis plans, review statistical analysis plans written by other statisticians, perform and oversee data analysis and validation, and interpret analyses.
Prepare for and attend meetings with regulatory agencies.
Work with biostatistics compound/therapeutic area lead, peer management, and employees to develop, implement, and maintain department standards and practices.
Review timelines and analysis plans for CRO work to ensure timeliness and quality deliveries.

Review and validate CRO deliverables.
Act as the statistical subject matter expert with medical writers and other colleagues in the production of clinical reports, integrated summaries, and other documents.
Respond to statistical questions from regulatory agencies.

Required Knowledge, Skills, and Abilities

Knowledge of clinical trial design and analysis, including experience with complex statistical methods and models, including statistical principles and methodology and principles of statistical inference, including hypothesis testing and deriving estimates, parametric and non-parametric models and techniques, principles of sample size calculations for comparing two arms, principles of design of experiments in introducing conditions designed to affect an outcome of interest, and phase II-IV clinical trial data analysis.
Experience in using SAS and R; knowledge of other statistical applications and programming languages a plus.
Knowledge of applicable regulatory requirements and guidelines, e.g., ICH Guidelines and drug development regulatory requirements as they relate to statistics, including statistical contributions to marketing applications and CDISC standards.
Able to work in a fast-paced, flexible, team-oriented environment.
Possess excellent interpersonal and communication skills (written and verbal).
Strong attention to detail with a view to bring studies to a quality conclusion.
Flexible, positive, creative thinker, good communicator.
Work without close supervision. Well-developed time management skills are important.

Required/Preferred Education and Licenses

MS or MPH in statistics, mathematics, or a related discipline with a statistical focus and > 4 years of experience in pharmaceutical or biotechnology industry.
PhD in statistics, mathematics, or a related discipline with a statistical focus and > 2 years of experience in the pharmaceutical or biotechnology industry.
Knowledge of drug development regulations pertinent to statistical analysis.
Knowledge of the oncology or hematology therapeutic area is preferred
Bayesian and adaptive design experience is preferred.
Proficient SAS & R programming skills, solid understanding of CDISC models and standards.
Excellent writing and communication skills, demonstrated leadership abilities and excellent interpersonal skills.

#LI-Remote

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.

FOR US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $156,000.00 - $234,000.00

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate‘s expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company‘s Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz‘s Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html.

Senior Principal Statistician (Hiring Immediately)

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Brief Description:

Essential Functions

Participate in department and cross-functional meetings to optimize clinical study designs, endpoints, and analysis strategies in protocols.
Collaborate with cross-functional team members to meet study any recurring report timelines.
Support the development and implementation of study protocols.
Review and provide input to data capture systems and participate in their validation.
Develop statistical programs as necessary to simulate clinical trial design operating characteristics, perform analysis, prepare data displays, verify data accuracy and validity of analyses performed by statistical programming.
Write statistical analysis plans, review statistical analysis plans written by other statisticians, perform and oversee data analysis and validation, and interpret analyses.
Prepare for and attend meetings with regulatory agencies.
Work with biostatistics compound/therapeutic area lead, peer management, and employees to develop, implement, and maintain department standards and practices.
Review timelines and analysis plans for CRO work to ensure timeliness and quality deliveries.

Review and validate CRO deliverables.
Act as the statistical subject matter expert with medical writers and other colleagues in the production of clinical reports, integrated summaries, and other documents.
Respond to statistical questions from regulatory agencies.

Required Knowledge, Skills, and Abilities

Knowledge of clinical trial design and analysis, including experience with complex statistical methods and models, including statistical principles and methodology and principles of statistical inference, including hypothesis testing and deriving estimates, parametric and non-parametric models and techniques, principles of sample size calculations for comparing two arms, principles of design of experiments in introducing conditions designed to affect an outcome of interest, and phase II-IV clinical trial data analysis.
Experience in using SAS and R; knowledge of other statistical applications and programming languages a plus.
Knowledge of applicable regulatory requirements and guidelines, e.g., ICH Guidelines and drug development regulatory requirements as they relate to statistics, including statistical contributions to marketing applications and CDISC standards.
Able to work in a fast-paced, flexible, team-oriented environment.
Possess excellent interpersonal and communication skills (written and verbal).
Strong attention to detail with a view to bring studies to a quality conclusion.
Flexible, positive, creative thinker, good communicator.
Work without close supervision. Well-developed time management skills are important.

Required/Preferred Education and Licenses

MS or MPH in statistics, mathematics, or a related discipline with a statistical focus and > 4 years of experience in pharmaceutical or biotechnology industry.
PhD in statistics, mathematics, or a related discipline with a statistical focus and > 2 years of experience in the pharmaceutical or biotechnology industry.
Knowledge of drug development regulations pertinent to statistical analysis.
Knowledge of the oncology or hematology therapeutic area is preferred
Bayesian and adaptive design experience is preferred.
Proficient SAS & R programming skills, solid understanding of CDISC models and standards.
Excellent writing and communication skills, demonstrated leadership abilities and excellent interpersonal skills.

#LI-Remote

FOR US BASED CANDIDATES ONLY

RESTAURANT GENERAL MANAGER

Sat, 04 Jul 2026 00:00:00 GMT

RESTAURANT GENERAL MANAGER

LEAD WITH HEART. GROW WITH PURPOSE. INSPIRE YOUR TEAM.

You are applying for work with a Franchisee of Taco Bell, not Taco Bell Corporate or any of its affiliates. If hired, the Franchisee will be your employer. Franchisees are independent business owners who create their own compensation, benefits, and policies.

ABOUT US:

We believe Great Restaurants are built on more than Great Good. They are built on Great People, Positive Energy, and a Culture that celebrates Growth, Togetherness, and Bold Thinking. Our Goal is to create a workplace where everyone feels Supported, Empowered, and Inspired to bring their best self to work every day.

As a Franchise Organization, we take pride in developing Leaders who care about their Teams, their Guests, and their Communities. When you join us, you are joining a Family that invests in People First.

WHO WE’RE LOOKING FOR:

We are looking for a Dynamic, High Caliber Restaurant General Manager who brings Passion, Purpose, and proven Leadership Experience from a fast food, quick service, or full-service restaurant environment. Someone who thrives in fast paced operations, builds Strong Teams, and leads with Heart while driving Outstanding Results.

If you are the type of Leader who sets the Tone, energizes the Team, and elevates every Guest Interaction, you will feel right at home here.

WHAT YOU WILL DO:

As the Restaurant General Manager, you will be the center of the restaurant’s success. You will create an environment where Team Members feel supported, guests feel welcomed, and the restaurant runs with excellence.

YOU WILL:

Champion a Positive Culture built on Teamwork, Hospitality, and Mutual Respect!

Recruit, Hire, Train, and Coach a high performing Team!

Provide clear Direction, Encouragement, and Accountability!

Inspire your Team to deliver Fast, Friendly, Accurate Service!

Ensure Operational Excellence, Food Safety, and Brand Standards!

Manage restaurant P&L, labor, and inventory with strategic insight!

Solve problems with Empathy, Confidence, and Professionalism!

Celebrate Victories, develop Future Leaders, and make an Impact every day!

WHAT YOU BRING:

2–4 years of Leadership Experience in a high-volume fast food, QSR, or restaurant setting

A Passion for developing People and building strong, engaged Teams

Experience of Profit & Loss Accountability

Effective Communication, Coaching, and Decision-Making Skills

A commitment to Hospitality, Quality, and Operational Excellence

High School Diploma or GED required (College Degree preferred)

Must be at least 21 years old with dependable transportation

Ability to pass background and drug screening

PHYSICAL EXPECTATIONS:

Because this is a hands-on Leadership Role, you will need to be able to:

Stand, walk, lift 50 lbs., and perform physical tasks throughout your Shift
Keep the Restaurant and grounds Clean and Welcoming
Assist Team Members during peak periods as needed

WHY YOU WILL LOVE IT HERE:

You will join a Team that Values:

People First Leadership
Career Growth and Internal Promotion
A Fun, Supportive, Energetic Work Environment
A chance to Lead with Passion and Purpose.
Opportunities to have an influence on both your Team and your Community.

This is more than a Job, it is the next step in Meaningful, rewarding Leadership Care.

Senior Director, Oncology Pharmacology (Hiring Immediately)

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Brief Description

This individual will be responsible for leading scientific team members assigned to oncology assets ranging from discovery through regulatory approval.
This individual will both manage the oncology pharmacology team and serve a lead on one or more programs themselves.
Primary responsibilities of the oncology pharmacology team include establishing efficacy in relevant disease models, demonstrating differentiation relative to relevant comparators, determining PK/PD/efficacy relationships, characterizing mechanisms of action, identifying predictive disease models, indications, and biomarkers, driving preclinical discovery, supporting research and development of Jazz products and drug candidates overall, and designing and executing studies that address clinically relevant priorities.
Operational tasks include designing and executing experiments that are outsourced or performed by in-house bench researchers or academic collaborators, reviewing and contributing to clinical protocols, reviewing and authoring technical reports, coauthoring sections of regulatory documents ranging from IND to NDA/BLA submissions, and communicating relevant research at internal and external forums.
The oncology pharmacology team cross-functional, including participation in matrix teams assigned to specific products that include but are not limited to Clinical Development, Bioanalytical, Toxicology, Clinical Pharmacology, Biomarkers Regulatory Affairs, and Project Management.
Collaborate with and represent ORP on internal teams—to design, develop, implement, and oversee execution of strategies and experiments supporting nonclinical studies in hematologic malignancies and solid tumors.

Essential Functions

Design and execute experiments to elucidate efficacy, tolerability, mechanism of action, and biomarkers associated with complex combinations of multiple therapeutic modalities (small molecules, biologics, ADCs, bi-specifics, cell therapies, and other emerging platforms).
Critically evaluate biochemical and cellular assays.
Communicate effectively across JAZZ functional teams, highly matrixed, cross functional environments.
Demonstrate strong interpersonal, negotiation, and influence skills.
Independently develop experimental strategies, analyze data, and present results to non‑clinical and governance-level teams.
Collaborate with CROs to outsource studies, develop protocols, manage timelines and budgets, and partner with academic labs for Jazz sponsored research.
Serve as a project team leader and/or as lead pharmacology representative across various oncology programs,
Mentor junior scientists and providing scientific leadership and professional growth opportunities.

Required Knowledge, Skills, and Abilities

Industry experience evaluating therapeutic potential of drug candidates from hit to lead optimization through IND enabling studies, with deep expertise in oncology drug development.
Broad background in preclinical oncology with strong familiarity with emerging therapeutic modalities, competitive landscapes, and strategic assessment of diverse drug mechanisms.
Extensive experience in Immuno Oncology (I/O), including I/O relevant in vivo and in vitro models, immune cell biology, and integration of immunological endpoints into pharmacology programs.
Demonstrated experience working across multiple drug modalities, including small molecules, biologics, ADCs, bi-specifics, T cell engagers, cell and gene therapies, and RNA based therapeutics.
Strong foundational understanding of the interdependencies between Nonclinical Pharmacology, Toxicology, DMPK, and Clinical Pharmacology, including how these functions integrate to enable successful dose selection, therapeutic index characterization, risk assessment, and translational strategy.
Deep understanding of cancer signaling pathways and their therapeutic exploitation.
Proven experience leading multiple complex pharmacology programs at diverse CROs, including GLP and non-GLP environments.
Expertise designing and executing studies evaluating efficacy, tolerability, mechanism of action, and biomarker strategies for small molecule and biologic agents.
Ability to integrate preclinical and clinical datasets, innovate, and apply novel methodologies to advance therapeutic programs.
Proficiency with analytical tools (e.g., GraphPad Prism) and biomarker data analysis.
Direct people management experience, including mentorship, performance development, and leadership of scientific teams.
Strong leadership qualities, self motivation, and demonstrated success networking across internal teams, academia, industry, and regulatory agencies.
Excellent ability to assess program needs, oversee CRO activities, develop/review protocols, monitor execution, interpret results, and prepare high quality reports for regulatory submissions.
Experience authoring nonclinical components of IND, NDA/BLA/MAA submissions, briefing packages, DSURs, IBs, and fast track designation documents, with proven ability to ensure alignment and scientific rigor.
Strong project management skills with the ability to manage multiple complex programs simultaneously.
Demonstrated success leading in fast paced, highly matrixed environments, aligning diverse stakeholders and driving decision making.
Strong analytical and creative problem-solving skills.
Embody and model Jazz core values.

Required/Preferred Education and Licenses

Ph.D. in biology, biochemistry, immunology, pharmacology, or a related discipline, with experience leading early oncology programs and developing nonclinical models for characterizing therapeutic efficacy and pharmacodynamics, including substantial oncology and immuno-oncology experience.

#LI-SM1

#LI-remote

FOR US BASED CANDIDATES ONLY

Restaurant General Manager

Sat, 04 Jul 2026 00:00:00 GMT

‘LEAD WITH HEART. GROW WITH PURPOSE. INSPIRE YOUR TEAM.

ABOUT US:

WHO WE’RE LOOKING FOR:

If you are the type of Leader who sets the Tone, energizes the Team, and elevates every Guest Interaction, you will feel right at home here.

WHAT YOU WILL DO:

YOU WILL:

Champion a Positive Culture built on Teamwork, Hospitality, and Mutual Respect!

Recruit, Hire, Train, and Coach a high performing Team!

Provide clear Direction, Encouragement, and Accountability!

Inspire your Team to deliver Fast, Friendly, Accurate Service!

Ensure Operational Excellence, Food Safety, and Brand Standards!

Manage restaurant P&L, labor, and inventory with strategic insight!

Solve problems with Empathy, Confidence, and Professionalism!

Celebrate Victories, develop Future Leaders, and make an Impact every day!

WHAT YOU BRING:

2–4 years of Leadership Experience in a high-volume fast food, QSR, or restaurant setting

A Passion for developing People and building strong, engaged Teams

Experience of Profit & Loss Accountability

Effective Communication, Coaching, and Decision-Making Skills

A commitment to Hospitality, Quality, and Operational Excellence

High School Diploma or GED required (College Degree preferred)

Must be at least 21 years old with dependable transportation

Ability to pass background and drug screening

PHYSICAL EXPECTATIONS:

Because this is a hands-on Leadership Role, you will need to be able to:

Stand, walk, lift 50 lbs., and perform physical tasks throughout your Shift
Keep the Restaurant and grounds Clean and Welcoming
Assist Team Members during peak periods as needed

WHY YOU WILL LOVE IT HERE:

You will join a Team that Values:

People First Leadership
Career Growth and Internal Promotion
A Fun, Supportive, Energetic Work Environment
A chance to Lead with Passion and Purpose.
Opportunities to have an influence on both your Team and your Community.

This is more than a Job, it is the next step in Meaningful, rewarding Leadership Care.

Director, Clinical Development, Neuroscience (Hiring Immedia...

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Brief Description

The Director, Clinical Development, will join a growing team in the therapeutic areas of Neuroscience. Responsibilities include clinical leadership of development programs, medical monitoring of clinical trials (if MD), contributing to CNS clinical development strategy, supporting regulatory submissions, and representing clinical development in multidisciplinary teams within R&D.

Essential Functions

Provide leadership and medical/scientific input for clinical programs, clinical protocols in development, ongoing clinical trials (Phase 2, Phase 3) , clinical study reports and regulatory documents.
Serve as medical monitor on trials for products under development in CNS/neurology (if MD or appropriate per role).
Provide clinical oversight during clinical programs and make recommendations based on findings to team, as needed.
Provide strategic input on new product concepts, long-range strategic plans and licensing opportunities in CNS.
Collaborate closely within clinical development and with cross-functional team members including in clinical operations, regulatory affairs, drug safety and pharmacovigilance, and quality to facilitate the execution of phase 2 and phase 3 clinical trials and programs.
Collaborate closely with study investigators on clinical trial eligibility and subject and patient safety issues.
Engage external experts to obtain scientific input into clinical program development.
Prepare clinical data and clinical program presentations
Review, interpret, and approve safety and efficacy data in clinical study reports, regulatory documents and submissions related to clinical trials (e.g., IND and NDA).
Review publication-related materials on Jazz Pharmaceuticals sponsored studies.

Required Knowledge, Skills, and Abilities

Clinical/scientific research experience required, with neuroscience expertise, epilepsy expertise preferred.
Experience working in a pharma/biotech company, CRO, or other clinical research related vendor preferred.

Ability to effectively lead cross functional teams and successfully leverage internal and external partnerships
Experience in preparation of regulatory submissions (INDs and NDAs) to US and European regulatory agencies. Lead preparation of clinical portions of relevant regulatory documents.

Excellent oral and written communication skills.
Knowledge of GCP, drug safety, MedDRA safety coding, and pharmacovigilance processes (as appropriate per role).
Collaborative and flexible in personal interactions at all levels of the company.
Ability to train other physicians/scientists a plus.
Ability to work proactively and effectively, with demonstrated creative problem solving skills.

Travel required (up to 5-20% of time)

Required/Preferred Education and Licenses

Medical degree, MD or advanced degree in biological sciences e.g. PhD or Pharm D with drug development experience in Neuroscience, experience in epilepsy is highly advantageous.
Board Certification in Neurology, or equivalent CNS training is required US licensure and/or clinical practice experience preferred
US licensure and/or clinical practice experience preferred

#LI-SM1

#LI-remote

FOR US BASED CANDIDATES ONLY

Senior Director, Oncology Pharmacology (Hiring Immediately)

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Brief Description

This individual will be responsible for leading scientific team members assigned to oncology assets ranging from discovery through regulatory approval.
This individual will both manage the oncology pharmacology team and serve a lead on one or more programs themselves.
Primary responsibilities of the oncology pharmacology team include establishing efficacy in relevant disease models, demonstrating differentiation relative to relevant comparators, determining PK/PD/efficacy relationships, characterizing mechanisms of action, identifying predictive disease models, indications, and biomarkers, driving preclinical discovery, supporting research and development of Jazz products and drug candidates overall, and designing and executing studies that address clinically relevant priorities.
Operational tasks include designing and executing experiments that are outsourced or performed by in-house bench researchers or academic collaborators, reviewing and contributing to clinical protocols, reviewing and authoring technical reports, coauthoring sections of regulatory documents ranging from IND to NDA/BLA submissions, and communicating relevant research at internal and external forums.
The oncology pharmacology team cross-functional, including participation in matrix teams assigned to specific products that include but are not limited to Clinical Development, Bioanalytical, Toxicology, Clinical Pharmacology, Biomarkers Regulatory Affairs, and Project Management.
Collaborate with and represent ORP on internal teams—to design, develop, implement, and oversee execution of strategies and experiments supporting nonclinical studies in hematologic malignancies and solid tumors.

Essential Functions

Design and execute experiments to elucidate efficacy, tolerability, mechanism of action, and biomarkers associated with complex combinations of multiple therapeutic modalities (small molecules, biologics, ADCs, bi-specifics, cell therapies, and other emerging platforms).
Critically evaluate biochemical and cellular assays.
Communicate effectively across JAZZ functional teams, highly matrixed, cross functional environments.
Demonstrate strong interpersonal, negotiation, and influence skills.
Independently develop experimental strategies, analyze data, and present results to non‑clinical and governance-level teams.
Collaborate with CROs to outsource studies, develop protocols, manage timelines and budgets, and partner with academic labs for Jazz sponsored research.
Serve as a project team leader and/or as lead pharmacology representative across various oncology programs,
Mentor junior scientists and providing scientific leadership and professional growth opportunities.

Required Knowledge, Skills, and Abilities

Industry experience evaluating therapeutic potential of drug candidates from hit to lead optimization through IND enabling studies, with deep expertise in oncology drug development.
Broad background in preclinical oncology with strong familiarity with emerging therapeutic modalities, competitive landscapes, and strategic assessment of diverse drug mechanisms.
Extensive experience in Immuno Oncology (I/O), including I/O relevant in vivo and in vitro models, immune cell biology, and integration of immunological endpoints into pharmacology programs.
Demonstrated experience working across multiple drug modalities, including small molecules, biologics, ADCs, bi-specifics, T cell engagers, cell and gene therapies, and RNA based therapeutics.
Strong foundational understanding of the interdependencies between Nonclinical Pharmacology, Toxicology, DMPK, and Clinical Pharmacology, including how these functions integrate to enable successful dose selection, therapeutic index characterization, risk assessment, and translational strategy.
Deep understanding of cancer signaling pathways and their therapeutic exploitation.
Proven experience leading multiple complex pharmacology programs at diverse CROs, including GLP and non-GLP environments.
Expertise designing and executing studies evaluating efficacy, tolerability, mechanism of action, and biomarker strategies for small molecule and biologic agents.
Ability to integrate preclinical and clinical datasets, innovate, and apply novel methodologies to advance therapeutic programs.
Proficiency with analytical tools (e.g., GraphPad Prism) and biomarker data analysis.
Direct people management experience, including mentorship, performance development, and leadership of scientific teams.
Strong leadership qualities, self motivation, and demonstrated success networking across internal teams, academia, industry, and regulatory agencies.
Excellent ability to assess program needs, oversee CRO activities, develop/review protocols, monitor execution, interpret results, and prepare high quality reports for regulatory submissions.
Experience authoring nonclinical components of IND, NDA/BLA/MAA submissions, briefing packages, DSURs, IBs, and fast track designation documents, with proven ability to ensure alignment and scientific rigor.
Strong project management skills with the ability to manage multiple complex programs simultaneously.
Demonstrated success leading in fast paced, highly matrixed environments, aligning diverse stakeholders and driving decision making.
Strong analytical and creative problem-solving skills.
Embody and model Jazz core values.

Required/Preferred Education and Licenses

Ph.D. in biology, biochemistry, immunology, pharmacology, or a related discipline, with experience leading early oncology programs and developing nonclinical models for characterizing therapeutic efficacy and pharmacodynamics, including substantial oncology and immuno-oncology experience.

#LI-SM1

#LI-remote

FOR US BASED CANDIDATES ONLY

Food Champion

Sat, 04 Jul 2026 00:00:00 GMT

The Taco Bell Food Champion plays and important role in producing tasty food in a quick and efficient manner. YOU will set the tone for the Taco Bell customer experience and bring the great Taco Bell tastes to life. Your role as a Food Champion is to feed people‘s lives with Más. You‘ll feed customers with great tasting food and provide great service so our customers keep coming back! You‘re a representation of the brand in everything you do.

This is a very important job for a friendly, helpful individual who enjoys working in a fast-paced environment and paying attention to detail. Key responsibilities include taking orders or preparing food, assisting in resolving any service or food issues, maintaining food-safety standards and maintaining a clean, safe work and dining environment.

A successful candidate will have a clean and tidy appearance, good work habits and a positive attitude. If you want to build a great career while providing fast, fun and friendly service to our customers, Taco Bell is the place to learn, grow and succeed!

Food Champion Responsibilities:

On the Line
Prepare food ingredients
Assemble food orders and check to make sure orders are correct
Package products
Maintain a clean, safe work environment
Be knowledgeable about Menu Items and Promotions
Training

Advisor Software Engineer (AI/ML)

Sat, 04 Jul 2026 00:00:00 GMT

Playing an essential role in the U.S. economy, Fannie Mae is foundational to housing finance. Here, your expertise can help fuel purpose-driven innovation that expands access to homeownership and affordable rental housing across the country. Join Fannie Mae to grow your career and help people find a place to call home.

Job Description

As a valued contributor to our team, you will design, produce, test, or implement software, technology, or processes across multiple projects, programs, or products, as well as create and maintain IT architecture, large scale data stores, and cloud-based systems.

THE IMPACT YOU WILL MAKE

The Advisor Software Engineer (AI/ML) role will offer you the flexibility to make each day your own, while working alongside people who care so that you can deliver on the following responsibilities:

Determine the needs of the customer groups across multiple projects, programs, or products while identifying and resolving conflicting or complementary needs across customer groups.
Design and develop software solutions to meet needs and may also lead matrixed teams.
Apply extensive expertise in process-driven approach in designing solutions.
Implement new software technology and coordinate simultaneous implementation tasks across teams.
Oversee the maintenance of existing software

There is 1 opening for this position which can be based in our Reston, VA office.

An Advisor role at Fannie Mae is on the same level as a Manager, but in an IC capacity.

THE EXPERIENCE YOU BRING TO THE TEAM

Minimum Required Experiences

6 years of hands-on software engineering experience designing, developing, and maintaining scalable enterprise applications and cloud-native solutions.
Strong proficiency in Python development, including backend services, APIs, automation, data processing workflows, and production-ready AI/ML applications.
Strong skills in system design and architecture, including scalable, resilient, secure, and maintainable solution design.
Experience building API-driven solutions, including REST APIs, microservices, service orchestration, secure API development, and enterprise system integrations.
Hands-on experience with AWS cloud-native development, including serverless, event-driven, containerized, and distributed application patterns.
Experience with SQL and data platforms, including PostgreSQL, Snowflake, or similar relational and analytical database technologies.
Deep understanding of the software development lifecycle, including requirements analysis, design, development, testing, deployment, production support, and maintenance.
Experience with engineering best practices, including secure coding, code reviews, automated testing, CI/CD, observability, performance tuning, and production issue resolution.
Experience collaborating with technical and business stakeholders, including translating business needs into technical solutions and communicating risks, trade-offs, and delivery impacts.

Desired Experiences

Bachelor’s or master’s degree in Computer Science, Engineering, Information Technology, Data Science, Machine Learning, Artificial Intelligence, or a related field.
Experience designing and delivering AI-enabled enterprise software solutions, including GenAI applications, intelligent automation, AI-assisted workflows, and AI-driven decision support.
Experience with MLOps, vector databases, embedding-based search, MCP-based tool integration, and enterprise AI governance practices.
Experience writing technical papers, invention disclosures, patent-supporting documentation, or reusable engineering playbooks for emerging technology solutions.
Experience with testing strategies and tools, including unit, integration, functional, regression, and performance testing.
Experience with Scaled Agile Framework, Agile methodology, cybersecurity vulnerability remediation, and enterprise delivery practices.
Strong relationship management skills with the ability to collaborate across stakeholders, influence outcomes, and support strategic enterprise technology initiatives.

AWS Cloud Technologies

Hands-on AWS software engineering experience, including application development using AWS service APIs, AWS CLI, AWS SDKs, and cloud-native deployment patterns.
Hands-on experience with core AWS services, including AWS Lambda, Amazon S3, Amazon EC2, Amazon API Gateway, IAM, CloudWatch, EventBridge, SQS, SNS, and Step Functions.
Experience with AWS AI/ML services, including Amazon SageMaker, Amazon Bedrock, and AWS-based model deployment or inference patterns.
Experience with containers and DevOps practices, including Docker, Kubernetes, ECS/EKS, CI/CD pipelines, automated testing, and release management.
Understanding of cloud security and compliance practices, including IAM, encryption, secrets management, vulnerability remediation, logging, and secure application design.

AI/ML and GenAI Technologies

Hands-on experience in machine learning, AI engineering, data science, or applied AI solution development.
Hands-on experience with Generative AI and Large Language Models, including OpenAI, Anthropic, Cohere, Amazon Bedrock, or similar enterprise AI platforms.
Strong proficiency in Python and AI/ML libraries, including PyTorch, TensorFlow, Scikit-learn, Pandas, NumPy, and related ML frameworks.
Experience building Retrieval-Augmented Generation solutions, including embeddings, vector databases, semantic search, document retrieval, chunking strategies, prompt grounding, and response evaluation.
Experience with LLM application patterns, including prompt engineering, guardrails, model evaluation, tool/function calling, agentic workflows, and responsible AI considerations.
Familiarity with AI application frameworks and tools, such as LangChain, LlamaIndex, FastAPI, MCP tools, vector databases, and API-based AI service integration.
Experience with model development and deployment practices, including feature engineering, model serving, model monitoring, MLOps, and productionizing AI/ML capabilities.

Leadership and Innovation Skills

Proven experience leading technical delivery within software engineering teams, including solution direction, task assignment, progress monitoring, issue resolution, and delivery accountability.
Experience mentoring and coaching engineers, including technical guidance, code review feedback, design support, and professional development.
Ability to influence technical decisions and engineering practices, including architecture discussions, design trade-offs, quality improvements, and adoption of modern AI/ML and cloud engineering standards.
Experience partnering with product owners, architects, business stakeholders, risk, security, and operations teams to deliver solutions aligned with business outcomes and enterprise standards.
Ability to produce high-quality technical documentation, including architecture papers, solution design documents, technical white papers, AI/ML implementation guides, and executive-ready technical summaries.
Experience contributing to innovation artifacts, such as invention disclosures, patent-supporting technical writeups, proof-of-concept documentation, and publication-ready technical papers when applicable.

Enterprise Risk Technology - Software Engineering - Advisor

155,000.00 - 209,000.00

JR2645

Qualifications

Amazon Web Services (AWS), Amazon Web Services (AWS), Atlassian JIRA, AWS Machine Learning, Business Process Management Skills, Cloud Technology, Communicating in Technical Writing, Communication, Computer Vision, Configuration Management (CM), Coordination, Customer and Market Insights, Data Analysis Interpretation, Data Mining, Data Visualization, Enterprise Information Security Architecture, Gradient Boosting Algorithms, Identity Management (IdM), Internal Auditing, Knowledge Management, Machine Learning (AI), Model Explainability, Multi-modal Machine Learning Models, Natural Language Processing (NLP), Neural Networks Methods and Algorithms {+ 20 more}

Education:

Master‘s Level Degree: Artificial Intelligence and Robotics (Required)

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For most roles, employees are expected to work onsite on a regular basis at their designated office location. In-office work cadence is determined by your manager. Proximity within a reasonable commute to your designated office location is preferred unless the job is noted as open to remote.

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The hiring range for this role is set forth below. Final salaries will generally vary within that range based on factors that include but are not limited to, skill set, depth of experience, certifications, and other relevant qualifications. This position is eligible to participate in a Fannie Mae incentive program (subject to the terms of the program). As part of our comprehensive benefits package, Fannie Mae offers a broad range of Health, Life, Voluntary Lifestyle, and other benefits and perks that enhance an employee‘s physical, mental, emotional, and financial well-being. See more here.

Requisition compensation:

155000

209000

Senior Director, Oncology Pharmacology (Hiring Immediately)

Sat, 04 Jul 2026 00:00:00 GMT

If you are a current Jazz employee please apply via the Internal Career site.

Brief Description

This individual will be responsible for leading scientific team members assigned to oncology assets ranging from discovery through regulatory approval.
This individual will both manage the oncology pharmacology team and serve a lead on one or more programs themselves.
Primary responsibilities of the oncology pharmacology team include establishing efficacy in relevant disease models, demonstrating differentiation relative to relevant comparators, determining PK/PD/efficacy relationships, characterizing mechanisms of action, identifying predictive disease models, indications, and biomarkers, driving preclinical discovery, supporting research and development of Jazz products and drug candidates overall, and designing and executing studies that address clinically relevant priorities.
Operational tasks include designing and executing experiments that are outsourced or performed by in-house bench researchers or academic collaborators, reviewing and contributing to clinical protocols, reviewing and authoring technical reports, coauthoring sections of regulatory documents ranging from IND to NDA/BLA submissions, and communicating relevant research at internal and external forums.
The oncology pharmacology team cross-functional, including participation in matrix teams assigned to specific products that include but are not limited to Clinical Development, Bioanalytical, Toxicology, Clinical Pharmacology, Biomarkers Regulatory Affairs, and Project Management.
Collaborate with and represent ORP on internal teams—to design, develop, implement, and oversee execution of strategies and experiments supporting nonclinical studies in hematologic malignancies and solid tumors.

Essential Functions

Design and execute experiments to elucidate efficacy, tolerability, mechanism of action, and biomarkers associated with complex combinations of multiple therapeutic modalities (small molecules, biologics, ADCs, bi-specifics, cell therapies, and other emerging platforms).
Critically evaluate biochemical and cellular assays.
Communicate effectively across JAZZ functional teams, highly matrixed, cross functional environments.
Demonstrate strong interpersonal, negotiation, and influence skills.
Independently develop experimental strategies, analyze data, and present results to non‑clinical and governance-level teams.
Collaborate with CROs to outsource studies, develop protocols, manage timelines and budgets, and partner with academic labs for Jazz sponsored research.
Serve as a project team leader and/or as lead pharmacology representative across various oncology programs,
Mentor junior scientists and providing scientific leadership and professional growth opportunities.

Required Knowledge, Skills, and Abilities

Industry experience evaluating therapeutic potential of drug candidates from hit to lead optimization through IND enabling studies, with deep expertise in oncology drug development.
Broad background in preclinical oncology with strong familiarity with emerging therapeutic modalities, competitive landscapes, and strategic assessment of diverse drug mechanisms.
Extensive experience in Immuno Oncology (I/O), including I/O relevant in vivo and in vitro models, immune cell biology, and integration of immunological endpoints into pharmacology programs.
Demonstrated experience working across multiple drug modalities, including small molecules, biologics, ADCs, bi-specifics, T cell engagers, cell and gene therapies, and RNA based therapeutics.
Strong foundational understanding of the interdependencies between Nonclinical Pharmacology, Toxicology, DMPK, and Clinical Pharmacology, including how these functions integrate to enable successful dose selection, therapeutic index characterization, risk assessment, and translational strategy.
Deep understanding of cancer signaling pathways and their therapeutic exploitation.
Proven experience leading multiple complex pharmacology programs at diverse CROs, including GLP and non-GLP environments.
Expertise designing and executing studies evaluating efficacy, tolerability, mechanism of action, and biomarker strategies for small molecule and biologic agents.
Ability to integrate preclinical and clinical datasets, innovate, and apply novel methodologies to advance therapeutic programs.
Proficiency with analytical tools (e.g., GraphPad Prism) and biomarker data analysis.
Direct people management experience, including mentorship, performance development, and leadership of scientific teams.
Strong leadership qualities, self motivation, and demonstrated success networking across internal teams, academia, industry, and regulatory agencies.
Excellent ability to assess program needs, oversee CRO activities, develop/review protocols, monitor execution, interpret results, and prepare high quality reports for regulatory submissions.
Experience authoring nonclinical components of IND, NDA/BLA/MAA submissions, briefing packages, DSURs, IBs, and fast track designation documents, with proven ability to ensure alignment and scientific rigor.
Strong project management skills with the ability to manage multiple complex programs simultaneously.
Demonstrated success leading in fast paced, highly matrixed environments, aligning diverse stakeholders and driving decision making.
Strong analytical and creative problem-solving skills.
Embody and model Jazz core values.

Required/Preferred Education and Licenses

Ph.D. in biology, biochemistry, immunology, pharmacology, or a related discipline, with experience leading early oncology programs and developing nonclinical models for characterizing therapeutic efficacy and pharmacodynamics, including substantial oncology and immuno-oncology experience.

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